The mesenchymal stem cells therapy Diaries
IDO can be a charge-restricting enzyme for degrading tryptophan (Trp) to N-formylkynurenine. in addition to the cell–cell contact necessity for MSC to induce T-cell tolerance, the tradition medium also inhibits the proliferation of activated T lymphocytes, a paracrine outcome that partly is dependent upon the expression of IDO.188 The IDO-mediate